Uniques (Vanilla)
- Agonizer 1500 – Agonizer 9000 / Pain & Terror
- Crit – Tipping Moxxi
- Hail – Tipping Moxxi
- Shrieking Devil – Blinding Banshee
- The Hunt(ed) – Demoskaggons
- The Killing Word – Mouthpiece
Legendaries (DLC)
- Anarchy – Kukuwajack
- Boogeyman – Heavyweight Harker / World Drop
- Clairvoyance – Kritchy
- Cocky Bastard – Eista the Invincible
- Conductor (Zane) – Voltborn
- Critical Thug – Heavyweight Harker / World Drop
- Eternal Flame – Heavyweight Harker / World Drop
- Firefly – Heavyweight Harker / World Drop
- Flama Diddle – Wendigo
- Frozen Devil – Kukuwajack
- HOT Spring – Heavyweight Harker / World Drop
- Hotfoot Teddy – Heavyweight Harker / World Drop
- Hydrafrost – Shiverous
- Infernal Wish – Heavyweight Harker / World Drop
- Insider – Tom & Xam
- Kickcharger – Heavyweight Harker / World Drop
- Little Yeeti – Yeti
- Love Drill – Elanor
- Lunacy – Empowered Grawn
- Madcap – Heavyweight Harker / World Drop
- Mutant – Fungal Gorger
- Nothingness – Gmork
- Old God – Elenor
- Oldridian – Empowered Scholar
- Plasma Coil – Heavyweight Harker / World Drop
- Res – Heavyweight Harker / World Drop
- Sapper (Moze) – Empowered Grawn
- Seeryul Killer – Amach
- SF Force – DJ Spinsmouth
- Shocker – Voltborn
- Skullmasher – Eista the Invincible
- Soulrender – Tom & Xam
- Stauros Burn – Wendigo
- Stone (Amara) – Fungal Gorger
- Toboggan – Heavyweight Harker / World Drop
- Torch – Gmork
- Tr4iner (FL4K) – Shiverous
- Unseen Threat – Amach
- Void Rift – Empowered Scholar
Mayhem Levels
- Backburner – Agonizer 9000
Legendaries (Vanilla)
- Bangarang – Thunk
- Breath of the Dying – Blinding Banshee
- Destructo Spinner – Power Troopers Sapphire & Tourmaine
- Devoted – Brood Mother / Alacritous Vanda
- Firestorm (Grenade) – Aurelia
- Grave – Graveward
- Handsome Jackhammer – Handsome Jackie
- Hellwalker – Road Dog
- Loaded Dice – Agonizer 9000 / Pain
- Maggie – Turnkey Tim
- Monocle – Demoskaggons
- Night Hawkin – Demoskaggons Rakkman
- Otto Idol – Rachael the Anointed
- Psycho Stabber – Borman Nates
- Rectifier – Muldock, The Anointed
- Recursion – General Traunt
- Red Queen – Blinding Banshee
- Ruby’s Wrath – Chonk Stomp
- Splattergun – Road Dog
- Star Helix – Power Troopers Onyx, Ruby, and Citrine
- Surge – Power Troopers Onyx, Ruby, and Citrine)
- The Butcher – Raging Titan / Loot-O-Grams
- The Lob – Graveward
- Thunderball Fists – Power Troopers Onyx, Ruby, and Citrine
- Tran-Fusion – Power Troopers Sapphire & Tourmaline
- Try-Bolt – Manvark
- Vanquisher – Power Troopers Sapphire & Tourmaline
- Ward – Graveward
- White Elephant – Agonizer 9000 & Terror